Similac Advance Vs Pro Advance

If you’re one of those parents who have difficulty with feeding the right baby formula to your little one, you could learn something from our article. Similac’s two products, the Similac Advance and the Similac Pro Advance look the same, but they are actually different in some aspects.

If you’re looking to find out whether you should get Similac Advance or Pro Advance, this one can be a helpful article for you, as we break down their differences and mention their similarities.

Difference between Similac Advance and Pro Advance

Here are the worth-noting differences between the Similac Advance and the Similac Pro Advance:

Feature Similac Advance Similac Pro Advance
Non-GMO No Yes

If you are a conscious parent when it comes down to non-GMO products, you would probably pick the Similac Pro Advance instead of the Similac Advance. This is because the Similac Pro Advance is made without any GMOs as compared to the original version.

Generally speaking, non-GMO foods have been hailed by many parents and nutritionists because they are pure and made without much chemicals or artificial stuff. Non-GMO foods could have the following benefits:

  • Less likelihood of cancer
  • Fewer allergies
  • Doesn’t pile up antibiotic resistance
  • Can preserve internal organs
Feature Similac Advance Similac Pro Advance
Cow’s milk Regular cow’s milk Non-rBST cow’s milk (organic)

As we can see above, Similac Advance is made with regular cow’s milk while the Pro Advance is made with non-rBST cow’s milk, which means that it has a more organic formula than that of the Similac Advance.

  • Bovine somatotropin or rBST is a hormone that is injected into cows to make their production of milk much faster, much like putting up fertilizers for plants to make the crops grow and hasten harvest.
  • Although there haven’t been a lot of studies yet to prove that non-rBST treated cow’s milk is significantly better than regular cow’s milk, some parents do feel alarmed if their cows contain such hormones that aid the production of cow’s milk and they may not want that.
  • Having pure cow’s milk that isn’t treated with anything seemed like a better option for most parents, after all, to get the right nutrition for their baby.
Feature Similac Advance Similac Pro Advance
HMO Genetically modified HMO Has prebiotics in its HMO

When it comes down to the HMO, since they are both baby formulas, neither of them is derived from natural breast milk, of course, but Similac Pro Advance seems to have more nutrients that make it a little closer to regular breast milk. For instance, it has prebiotics in its HMO.

  • Human Milk Oligosaccharide, also known as HMO, is a nutrient that is present in a mother’s milk. Most baby formula brands like Similac have duplicated this in the lab so that the nutrients are almost very identical to the one found in regular breast milk.
  • The benefit of HMO is that it can give your child the right amount of immunity against sickness, which is definitely needed by babies who are still very young. Some of them also help the baby develop a less sensitive tummy.

Similarities between Similac Advance and Pro Advance

The Similac Advance and the Similac Pro Advance also have some things that are similar to each other, such as the following:

1. DHA. This is a type of nutrient that can help with your baby’s development, especially in their brains and function. You may often see DHA in many baby formulas as the marketing formula “to make your child smarter when they grow up”, although it’s just a case-to-case basis and still need proper parenting.

Nonetheless, DHA does have an important role in babies, since it is a type of omega-3 fatty acid. It can also help with their eyes and their overall development.

2. Lutein. The eyes are boosted with lutein, which can be important for a baby’s learning. If they have clearer eyes when they are young, they may be able to discern objects better and thus, they may become more advanced in development as compared to other babies.

3. Vitamin E. As we all know, vitamin E is an antioxidant that can help the skin glow better. Vitamin E is also present in Similac’s OptiGro exclusive blend so your baby could have a healthy skin as well when they drink that formula.

4. Good taste. The taste of both the Similac Pro Advance and the Similac Advance is almost reminiscent of the natural breast milk found in humans. This means that if you ever use either milk formula for your little one and you also breastfeed them at the same time, your baby won’t really be able to tell the difference.

This may be ideal for nursing moms who don’t really have all the time in the world to pump or don’t always have natural breast milk available. Having a baby formula at hand can be helpful in this situation, especially one that tastes much like natural mom’s milk.

5. HMOs. Both the Similac Pro Advance and the Similac Advance have HMOs, which are similar to the nutrient that is found in regular breast milk. It can help with your baby’s immune system so it’s safe to say that both Similac products can be great in maintaining your child’s health against most illnesses.


To wrap it up, we chose the Similac Pro Advance over the Similac Advance when it comes down to the HMO formulation, the non-rBST cow’s milk, and the non-GMO formulation of the milk. For meticulous parents who don’t like their babies being fed with genetically-modified ingredients, the Similac Pro Advance may be for you.

However, in the same way, both baby formulas are quite similar to natural breast milk, so you can definitely pick any of them if you are not very cautious about the GMO thing. Both do taste great and if you’re looking for a different brand that’s closest to breast milk taste, Similac is a way to go!

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